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MIT Chemistry Department
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| picture taken by Kathrin Winkler, San Diego 1997. |
In the past I was working on small-molecule-structures such like indigoid systems and organometallic compounds like metal-silizanes.
My Ph.D. dealed with methods development in both protein and small molecular crystallography:
The thesis is entiteled Problems of modern high-resolution single-crystal X-ray structure analysis and investigates some of the major problems of modern X-ray structure analysis, from crystallisation through data-collection and structure refinement to model validation. Giving several examples, it shows how to handle difficult structures, and how to deal with e.g. disorder or twinning. Thus, a picture is drawn, which presents the current situation of the method of single-crystal X-ray diffraction: where is crystallography today and how can it possibly develop in the near future.